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Combining Cationic Liposomal Delivery with MPL-TDM for Cysteine Protease Cocktail Vaccination against Leishmania donovani : Evidence for Antigen Synergy and Protection

BACKGROUND: With the paucity of new drugs and HIV co-infection, vaccination remains an unmet research priority to combat visceral leishmaniasis (VL) requiring strong cellular immunity. Protein vaccination often suffers from low immunogenicity and poor generation of memory T cells for long-lasting pr...

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Detalhes bibliográficos
Main Authors: Das, Amrita, Ali, Nahid
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140747/
https://ncbi.nlm.nih.gov/pubmed/25144181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003091
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