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Dual growth factor delivery from bilayered, biodegradable hydrogel composites for spatially-guided osteochondral tissue repair

The present work investigated the use of biodegradable hydrogel composite scaffolds, based on the macromer oligo(poly(ethylene glycol) fumarate) (OPF), to deliver growth factors for the repair of osteochondral tissue in a rabbit model. In particular, bilayered OPF composites were used to mimic the s...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lu, Steven, Lam, Johnny, Trachtenberg, Jordan E., Lee, Esther J., Seyednejad, Hajar, van den Beucken, Jeroen J. J. P., Tabata, Yasuhiko, Wong, Mark E., Jansen, John A., Mikos, Antonios G., Kasper, F. Kurtis
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140660/
https://ncbi.nlm.nih.gov/pubmed/25047629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2014.07.006
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