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A Model-Based Approach for Identifying Signatures of Ancient Balancing Selection in Genetic Data

While much effort has focused on detecting positive and negative directional selection in the human genome, relatively little work has been devoted to balancing selection. This lack of attention is likely due to the paucity of sophisticated methods for identifying sites under balancing selection. He...

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Detalhes bibliográficos
Main Authors: DeGiorgio, Michael, Lohmueller, Kirk E., Nielsen, Rasmus
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140648/
https://ncbi.nlm.nih.gov/pubmed/25144706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004561
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