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The First Total Synthesis of Sporiolide A

[Image: see text] The first total synthesis of the natural cytotoxic agent sporiolide A has been accomplished from D-glucal in 16 steps with 6.1% overall yield. Carbohydrates were applied as the chiral templates to manipulate the absolute configuration during the synthesis. Pyridinium chlorochromate...

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Autores principales: Du, Yuguo, Chen, Qi, Linhardt, Robert J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2006
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140563/
https://ncbi.nlm.nih.gov/pubmed/17064018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo0615504
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