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MicroRNA-200b Suppresses Arsenic-transformed Cell Migration by Targeting Protein Kinase Cα and Wnt5b-Protein Kinase Cα Positive Feedback Loop and Inhibiting Rac1 Activation

MicroRNA-200b (miR-200b) is a member of miR-200 family that has been found to inhibit cell migration and cancer metastasis; however, the underlying mechanism is not well understood. We previously reported that miR-200 expression is depleted in arsenic-transformed human bronchial epithelial cells wit...

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Detalhes bibliográficos
Main Authors: Wang, Zhishan, Humphries, Brock, Xiao, Hua, Jiang, Yiguo, Yang, Chengfeng
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140296/
https://ncbi.nlm.nih.gov/pubmed/24841200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.554246
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