Red blood cells stored for increasing periods produce progressive impairments in nitric oxide–mediated vasodilation

BACKGROUND: Clinical outcomes in transfused patients may be affected by the duration of blood storage, possibly due to red blood cell (RBC)-mediated disruption of nitric oxide (NO) signaling, a key regulator of vascular tone and blood flow. STUDY DESIGN AND METHODS: AS-1 RBC units stored up to 42 da...

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Main Authors: Alexander, Jason T., El-Ali, Alexander M., Newman, James L., Karatela, Sulaiman, Predmore, Benjamin L., Lefer, David J., Sutliff, Roy L., Roback, John D.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140194/
https://ncbi.nlm.nih.gov/pubmed/23480490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/trf.12111
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