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High-throughput DNA analysis shows the importance of methylation in the control of immune inflammatory gene transcription in chronic periodontitis

BACKGROUND: Chronic periodontitis represents a complex disease that is hard to control and is not completely understood. Evidence from past studies suggests that there is a key role for DNA methylation in the pathogenesis of periodontitis. However, all reports have applied technologies that investig...

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Main Authors: De Souza, Ana Paula, Planello, Aline Cristiane, Marques, Marcelo Rocha, De Carvalho, Daniel Diniz, Line, Sergio Roberto Peres
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140141/
https://ncbi.nlm.nih.gov/pubmed/25147584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1868-7083-6-15
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