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Genetic evidence suggests that Spata22 is required for the maintenance of Rad51 foci in mammalian meiosis

Meiotic nodules are the sites of double-stranded DNA break repair. Rpa is a single-stranded DNA-binding protein, and Rad51 is a protein that assists in the repair of DNA double strand breaks. The localisation of Rad51 to meiotic nodules before the localisation of Rpa in mice introduces the issue of...

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Detalhes bibliográficos
Main Authors: Ishishita, Satoshi, Matsuda, Yoichi, Kitada, Kazuhiro
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4139951/
https://ncbi.nlm.nih.gov/pubmed/25142975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep06148
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