A study protocol for a randomised open-label clinical trial of artesunate-mefloquine versus chloroquine in patients with non-severe Plasmodium knowlesi malaria in Sabah, Malaysia (ACT KNOW trial)

INTRODUCTION: Malaria due to Plasmodium knowlesi is reported throughout South-East Asia, and is the commonest cause of it in Malaysia. P. knowlesi replicates every 24 h and can cause severe disease and death. Current 2010 WHO Malaria Treatment Guidelines have no recommendations for the optimal treat...

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Detalhes bibliográficos
Main Authors: Grigg, M J, William, T, Dhanaraj, P, Menon, J, Barber, B E, von Seidlein, L, Rajahram, G, Price, R N, Anstey, N M, Yeo, T W
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2014
Assuntos:
Infectious Diseases
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4139630/
https://ncbi.nlm.nih.gov/pubmed/25138814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2014-006005
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