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Lead-Time Models Should Not Be Used to Estimate Overdiagnosis in Cancer Screening

Lead-time can mean two different things: Clinical lead-time is the lead-time for clinically relevant tumors; that is, those that are not overdiagnosed. Model-based lead-time is a theoretical construct where the time when the tumor would have caused symptoms is not limited by the person’s death. It i...

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Hlavní autoři: Zahl, Per-Henrik, Jørgensen, Karsten Juhl, Gøtzsche, Peter C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4139512/
https://ncbi.nlm.nih.gov/pubmed/24590736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11606-014-2812-2
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