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GBA2-Encoded β-Glucosidase Activity Is Involved in the Inflammatory Response to Pseudomonas aeruginosa

Current anti-inflammatory strategies for the treatment of pulmonary disease in cystic fibrosis (CF) are limited; thus, there is continued interest in identifying additional molecular targets for therapeutic intervention. Given the emerging role of sphingolipids (SLs) in various respiratory disorders...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Loberto, Nicoletta, Tebon, Maela, Lampronti, Ilaria, Marchetti, Nicola, Aureli, Massimo, Bassi, Rosaria, Giri, Maria Grazia, Bezzerri, Valentino, Lovato, Valentina, Cantù, Cinzia, Munari, Silvia, Cheng, Seng H., Cavazzini, Alberto, Gambari, Roberto, Sonnino, Sandro, Cabrini, Giulio, Dechecchi, Maria Cristina
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4139313/
https://ncbi.nlm.nih.gov/pubmed/25141135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104763
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