Borrelia burgdorferi Protein BBK32 Binds to Soluble Fibronectin via the N-terminal 70-kDa Region, Causing Fibronectin to Undergo Conformational Extension

BBK32 is a fibronectin (FN)-binding protein expressed on the cell surface of Borrelia burgdorferi, the causative agent of Lyme disease. There is conflicting information about where and how BBK32 interacts with FN. We have characterized interactions of a recombinant 86-mer polypeptide, “Bbk32,” compr...

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Detalhes bibliográficos
Main Authors: Harris, Gemma, Ma, Wenjiang, Maurer, Lisa M., Potts, Jennifer R., Mosher, Deane F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Glycobiology and Extracellular Matrices
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4139255/
https://ncbi.nlm.nih.gov/pubmed/24962582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.578419
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