A Cleavage-potentiated Fragment of Tear Lacritin Is Bactericidal

Antimicrobial peptides are important as the first line of innate defense, through their tendency to disrupt bacterial membranes or intracellular pathways and potentially as the next generation of antibiotics. How they protect wet epithelia is not entirely clear, with most individually inactive under...

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Detalles Bibliográficos
Autores principales: McKown, Robert L., Coleman Frazier, Erin V., Zadrozny, Kaneil K., Deleault, Andrea M., Raab, Ronald W., Ryan, Denise S., Sia, Rose K., Lee, Jae K., Laurie, Gordon W.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2014
Materias:
Microbiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4139230/
https://ncbi.nlm.nih.gov/pubmed/24942736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.570143
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