Andrographolide Induces Apoptosis of C6 Glioma Cells via the ERK-p53-Caspase 7-PARP Pathway

Background. Glioma is the most malignant tumor of the central nervous system. Efforts on the development of new chemotherapy are mandatory. Andrographolide (AND), a diterpenoid lactone isolated from the Andrographis paniculata, has been shown to have antitumor activities in several types of cancer c...

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Bibliographic Details
Main Authors: Yang, Shih-Hung, Wang, Seu-Mei, Syu, Jhih-Pu, Chen, Ying, Wang, Sheng-De, Peng, Yu-Sen, Kuo, Meng-Fai, Kung, Hsiu-Ni
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4139087/
https://ncbi.nlm.nih.gov/pubmed/25162007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/312847
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