Adipocyte ALK7 links nutrient overload to catecholamine resistance in obesity

Obesity is associated with blunted β-adrenoreceptor (β-AR)-mediated lipolysis and lipid oxidation in adipose tissue, but the mechanisms linking nutrient overload to catecholamine resistance are poorly understood. We report that targeted disruption of TGF-β superfamily receptor ALK7 alleviates diet-i...

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Detaylı Bibliyografya
Asıl Yazarlar: Guo, Tingqing, Marmol, Patricia, Moliner, Annalena, Björnholm, Marie, Zhang, Chao, Shokat, Kevan M, Ibanez, Carlos F
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: eLife Sciences Publications, Ltd 2014
Konular:
Human Biology and Medicine
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4139062/
https://ncbi.nlm.nih.gov/pubmed/25161195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.03245
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