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Synthesis and In Vitro Inhibition Effect of New Pyrido[2,3-d]pyrimidine Derivatives on Erythrocyte Carbonic Anhydrase I and II

In vitro inhibition effects of indolylchalcones and new pyrido[2,3-d]pyrimidine derivatives on purified human carbonic anhydrase I and II (hCA I and II) were investigated by using CO(2) as a substrate. The results showed that all compounds inhibited the hCA I and hCA II enzyme activities. Among all...

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Detalhes bibliográficos
Main Authors: Kuday, Hilal, Sonmez, Fatih, Bilen, Cigdem, Yavuz, Emre, Gençer, Nahit, Kucukislamoglu, Mustafa
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4139024/
https://ncbi.nlm.nih.gov/pubmed/25165709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/594879
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