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Mutations in yeast HAP2/HAP3 define a hybrid CCAAT box binding domain.

We describe a detailed genetic analysis of the DNA-binding regions in the HAP2/HAP3 CCAAT-binding heteromeric complex. The DNA-binding domain of HAP2 is shown to be a 21 residue region containing three critical histidines and three critical arginines. Mutation of an arginine at position 199 to leuci...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:EMBO J
Prif Awduron: Xing, Y, Fikes, J D, Guarente, L
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 1993
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC413902/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8223474/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1993.tb06153.x
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