DNA and redox state induced conformational changes in the DNA-binding domain of the Myb oncoprotein.

The DNA-binding domain of the oncoprotein Myb comprises three imperfect repeats, R1, R2 and R3. Only R2 and R3 are required for sequence-specific DNA-binding. Both are assumed to contain helix-turn-helix (HTH)-related motifs, but multidimensional heteronuclear NMR spectroscopy revealed a disordered...

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Main Authors: Myrset, A H, Bostad, A, Jamin, N, Lirsac, P N, Toma, F, Gabrielsen, O S
格式: Artigo
語言:Inglês
出版: 1993
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC413899/
https://ncbi.nlm.nih.gov/pubmed/8223472
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