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Open-complex formation by the host initiator, DnaA, at the origin of P1 plasmid replication.

Replication of P1 plasmid requires both the plasmid-specific initiator, RepA, and the host initiator, DnaA. Here we show that DnaA can make the P1 origin reactive to the single-strand specific reagents KMnO4 and mung bean nuclease. Addition of RepA further increased the KMnO4 reactivity of the origi...

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Détails bibliographiques
Publié dans:EMBO J
Auteurs principaux: Mukhopadhyay, G, Carr, K M, Kaguni, J M, Chattoraj, D K
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 1993
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC413885/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8223464/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1993.tb06143.x
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