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Developmental Programming: Prenatal Steroid Excess Disrupts Key Members of Intraovarian Steroidogenic Pathway in Sheep

Prenatal testosterone (T) excess disrupts ovarian cyclicity and increases circulating estradiol levels as well as follicular recruitment and persistence culminating in multifollicular ovary similar to women with polycystic ovary syndrome. We tested whether prenatal T excess, by androgenic or estroge...

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Main Authors: Padmanabhan, Vasantha, Salvetti, Natalia R., Matiller, Valentina, Ortega, Hugo H.
Format: Artigo
Jezik:Inglês
Izdano: Endocrine Society 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4138569/
https://ncbi.nlm.nih.gov/pubmed/25061847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2014-1266
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