Characterization of Neural Estrogen Signaling and Neurotrophic Changes in the Accelerated Ovarian Failure Mouse Model of Menopause

Accelerated ovarian failure (AOF) can be induced in young mice with low doses of 4-vinylcyclohexene diepoxide (VCD), modeling the hormone changes observed across menopause. We assessed markers of synaptic plasticity in the hippocampus, anxiety-like behavior, and spatial learning longitudinally at 4...

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Autores principales: Van Kempen, Tracey A., Gorecka, Jolanta, Gonzalez, Andreina D., Soeda, Fumio, Milner, Teresa A., Waters, Elizabeth M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Endocrine Society 2014
Materias:
Neuroendocrinology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4138565/
https://ncbi.nlm.nih.gov/pubmed/24926825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2014-1190
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