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Characterization of Neural Estrogen Signaling and Neurotrophic Changes in the Accelerated Ovarian Failure Mouse Model of Menopause

Accelerated ovarian failure (AOF) can be induced in young mice with low doses of 4-vinylcyclohexene diepoxide (VCD), modeling the hormone changes observed across menopause. We assessed markers of synaptic plasticity in the hippocampus, anxiety-like behavior, and spatial learning longitudinally at 4...

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Detalhes bibliográficos
Main Authors: Van Kempen, Tracey A., Gorecka, Jolanta, Gonzalez, Andreina D., Soeda, Fumio, Milner, Teresa A., Waters, Elizabeth M.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4138565/
https://ncbi.nlm.nih.gov/pubmed/24926825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2014-1190
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