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Rapid Remodeling of Tight Junctions During Paracellular Diapedesis in a Human Model of the Blood-Brain Barrier

Leukocyte transendothelial migration (TEM; diapedesis) is a critical event in immune surveillance and inflammation. Most TEM occurs at endothelial cell borders (paracellular). However, there is indirect evidence to suggest that at the tight junctions of the blood-brain barrier (BBB), leukocytes migr...

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Bibliographic Details
Main Authors: Winger, Ryan C., Koblinski, Jennifer E., Kanda, Takashi, Ransohoff, Richard M., Muller, William A.
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4138548/
https://ncbi.nlm.nih.gov/pubmed/25063869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400700
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