CDK11(p58) inhibits ERα-positive breast cancer invasion by targeting integrin β3 via the repression of ERα signaling

BACKGROUND: CDK11(p58), a Ser/Thr kinase that belongs to the cell division cycle 2-like 1 (CDC2L1) subfamily, is associated with cell cycle progression, tumorigenesis and apoptotic signaling. CDK11(p58) is also involved in the regulation of steroid receptors, such as androgen and estrogen receptors....

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Hauptverfasser: Chi, Yayun, Huang, Sheng, Wang, Lei, Zhou, Ruoji, Wang, Lisha, Xiao, Xiuying, Li, Dali, Cai, Ying, Zhou, Xiaoyan, Wu, Jiong
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4138392/
https://ncbi.nlm.nih.gov/pubmed/25106495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-577
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