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Ire1 Mediated mRNA Splicing in a C-Terminus Deletion Mutant of Drosophila Xbp1
The Unfolded Protein Response is a homeostatic mechanism that permits eukaryotic cells to cope with Endoplasmic Reticulum (ER) stress caused by excessive accumulation of misfolded proteins in the ER lumen. The more conserved branch of the UPR relies on an ER transmembrane enzyme, Ire1, which, upon E...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4138184/ https://ncbi.nlm.nih.gov/pubmed/25136861 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105588 |
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