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Bistable Expression of Virulence Genes in Salmonella Leads to the Formation of an Antibiotic-Tolerant Subpopulation

Phenotypic heterogeneity can confer clonal groups of organisms with new functionality. A paradigmatic example is the bistable expression of virulence genes in Salmonella typhimurium, which leads to phenotypically virulent and phenotypically avirulent subpopulations. The two subpopulations have been...

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Bibliografiske detaljer
Main Authors: Arnoldini, Markus, Vizcarra, Ima Avalos, Peña-Miller, Rafael, Stocker, Nicolas, Diard, Médéric, Vogel, Viola, Beardmore, Robert E., Hardt, Wolf-Dietrich, Ackermann, Martin
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4138020/
https://ncbi.nlm.nih.gov/pubmed/25136970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001928
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