Targeted disruption of the mouse cation-dependent mannose 6-phosphate receptor results in partial missorting of multiple lysosomal enzymes.

In mammalian cells two mannose 6-phosphate receptors (MPRs) are involved in lysosomal enzyme transport. To understand the precise function of the cation-dependent mannose 6-phosphate receptor (CD-MPR), one allele of the corresponding gene has been disrupted in mouse embryonic stem cells and homozygo...

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Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Ludwig, T, Ovitt, C E, Bauer, U, Hollinshead, M, Remmler, J, Lobel, P, Rüther, U, Hoflack, B
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC413788/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8262065/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1993.tb06218.x
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