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Dysregulation of the suppressor of cytokine signalling 3–signal transducer and activator of transcription-3 pathway in the aetiopathogenesis of Sjögren's syndrome

The suppressor of cytokine signalling 3 (SOCS3) negatively regulates the Janus kinase (JAK)/signal transducer and activator of transcription-3 (STAT-3)/interleukin (IL)-17 pathway. The proinflammatory cytokine IL-17 is over-expressed in Sjögren's syndrome (SS) and is a key factor in its pathoge...

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Bibliografske podrobnosti
Main Authors: Vartoukian, S R, Tilakaratne, W M, Seoudi, N, Bombardieri, M, Bergmeier, L, Tappuni, A R, Fortune, F
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137846/
https://ncbi.nlm.nih.gov/pubmed/24827536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12377
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