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Role of cathepsin B in regulating migration and invasion of fibroblast-like synoviocytes into inflamed tissue from patients with rheumatoid arthritis

Cathepsin B (CB), an important proteinase that participates in joint destruction in rheumatoid arthritis (RA), exhibits higher expression in fibroblast-like synoviocyte (FLS) of abnormal proliferative synovial tissues. Whether and how it affects the biological behaviours of RA-FLS, such as migration...

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Detalhes bibliográficos
Main Authors: Tong, B, Wan, B, Wei, Z, Wang, T, Zhao, P, Dou, Y, Lv, Z, Xia, Y, Dai, Y
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137842/
https://ncbi.nlm.nih.gov/pubmed/24749816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12357
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