TCDD INDUCES DERMAL ACCUMULATION OF KERATINOCYTE-DERIVED MATRIX METALLOPROTEINASE-10 IN AN ORGANOTYPIC MODEL OF HUMAN SKIN

The epidermis of skin is the first line of defense against the environment. A three dimensional model of human skin was used to investigate tissue-specific phenotypes induced by the environmental contaminant, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Continuous treatment of organotypic cultures of...

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Detalhes bibliográficos
Main Authors: De Abrew, K. Nadira, Thomas-Virnig, Christina L., Rasmussen, Cathy A., Bolterstein, Elyse A., Schlosser, Sandy J., Allen-Hoffmann, B. Lynn
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137792/
https://ncbi.nlm.nih.gov/pubmed/24576722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2014.02.010
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