Mutation of Tyr697, a GRB2-binding site, and Tyr721, a PI 3-kinase binding site, abrogates signal transduction by the murine CSF-1 receptor expressed in Rat-2 fibroblasts.

Lignende værker

• Tyr721 regulates specific binding of the CSF-1 receptor kinase insert to PI 3'-kinase SH2 domains: a model for SH2-mediated receptor-target interactions.
  af: Reedijk, M, et al.
  Udgivet: (1992)
• Identification of Tyr-703 and Tyr-936 as the primary association sites for Grb2 and Grb7 in the c-Kit/stem cell factor receptor.
  af: Thömmes, K, et al.
  Udgivet: (1999)
• Phosphorylation of receptor protein-tyrosine phosphatase alpha on Tyr789, a binding site for the SH3-SH2-SH3 adaptor protein GRB-2 in vivo.
  af: den Hertog, J, et al.
  Udgivet: (1994)
• Evidence for in vivo phosphorylation of the Grb2 SH2-domain binding site on focal adhesion kinase by Src-family protein-tyrosine kinases.
  af: Schlaepfer, D D, et al.
  Udgivet: (1996)
• Hierarchy of binding sites for Grb2 and Shc on the epidermal growth factor receptor.
  af: Batzer, A G, et al.
  Udgivet: (1994)