Definition and spatial location of mouse interleukin-2 residues that interact with its heterotrimeric receptor.

The high affinity receptor for interleukin-2 (IL-2) contains three subunits called IL-2R alpha, beta and gamma. A biological and receptor binding analysis based on 1393 different mutant mouse IL-2 (mIL-2) proteins was used to define the function of each of the 149 residues. By this genetic analysis,...

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Bibliografske podrobnosti
Main Authors: Zurawski, S M, Vega, F, Doyle, E L, Huyghe, B, Flaherty, K, McKay, D B, Zurawski, G
Format: Artigo
Jezik:Inglês
Izdano: 1993
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC413773/
https://ncbi.nlm.nih.gov/pubmed/8262055
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