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Evidence for Increased Levels of Positive and Negative Selection on the X Chromosome versus Autosomes in Humans
Partially recessive variants under positive selection are expected to go to fixation more quickly on the X chromosome as a result of hemizygosity, an effect known as faster-X. Conversely, purifying selection is expected to reduce substitution rates more effectively on the X chromosome. Previous work...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4137703/ https://ncbi.nlm.nih.gov/pubmed/24830675 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msu166 |
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