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In Vitro and In Vivo Effects of Suppressor of Cytokine Signalling 7 Knockdown in Breast Cancer: The Influence on Cellular Response to Hepatocyte Growth Factor

Purpose. Suppressor of cytokine signaling 7 (SOCS7) is a member of the SOCS family and is known to interact with phospholipase Cγ-1 (PLCγ-1), a key downstream mediator of the hepatocyte growth factor (HGF)/C-MET axis. Here, we report our observations of the effect of knocking down SOCS7 gene on the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sasi, Walid, Ye, Lin, Jiang, Wen G., Sharma, Anup K., Mokbel, Kefah
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137630/
https://ncbi.nlm.nih.gov/pubmed/25162020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/648040
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