PARP1-Driven Apoptosis in Chronic Lymphocytic Leukemia

Chronic lymphocytic leukemia (CLL) is considered a malignancy resulting from defects in apoptosis. For this reason, targeting apoptotic pathways in CLL may be valuable for its management. Poly [ADP-ribose] polymerase 1 (PARP1) is the main member of a family of nuclear enzymes that act as DNA damage...

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Main Authors: Diamantopoulos, Panagiotis T., Sofotasiou, Maria, Papadopoulou, Vasiliki, Polonyfi, Katerina, Iliakis, Theodoros, Viniou, Nora-Athina
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137605/
https://ncbi.nlm.nih.gov/pubmed/25161998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/106713
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