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Rethinking Molecular Mimicry in Rheumatic Heart Disease and Autoimmune Myocarditis: Laminin, Collagen IV, CAR, and B1AR as Initial Targets of Disease
Rationale: Molecular mimicry theory (MMT) suggests that epitope mimicry between pathogens and human proteins can activate autoimmune disease. Group A streptococci (GAS) mimics human cardiac myosin in rheumatic heart disease (RHD) and coxsackie viruses (CX) mimic actin in autoimmune myocarditis (AM)....
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| Formato: | Artigo |
| Idioma: | Inglês |
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Frontiers Media S.A.
2014
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4137453/ https://ncbi.nlm.nih.gov/pubmed/25191648 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fped.2014.00085 |
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