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Evidence for an Angiotensin-(1–7) Neuropeptidase Expressed in the Brain Medulla and CSF of Sheep

Angiotensin-(1–7) [Ang-(1–7)] is an alternative product of the brain renin-angiotensin system (RAS) that exhibits central actions to lower blood pressure and improve baroreflex sensitivity. We previously identified a peptidase that metabolizes Ang-(1–7) to the inactive metabolite product Ang-(1–4) i...

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Autors principals: Marshall, Allyson C., Pirro, Nancy T., Rose, James C., Diz, Debra I., Chappell, Mark C.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137327/
https://ncbi.nlm.nih.gov/pubmed/24661079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12720
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