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Learning-induced and stathmin-dependent changes in microtubule stability are critical for memory and disrupted in ageing
Changes in the stability of microtubules regulate many biological processes, but their role in memory remains unclear. Here we show that learning causes biphasic changes in the microtubule-associated network in the hippocampus. In the early phase, stathmin is dephosphorylated, enhancing its microtub...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4137320/ https://ncbi.nlm.nih.gov/pubmed/25007915 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5389 |
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