Depletion of functional ribosomal RNA operons in Escherichia coli causes increased expression of the remaining intact copies.

The synthesis of ribosomal RNA is a complex and highly regulated process. To study this process, we have used deletion-insertions to disrupt sequentially from one to four of the seven rRNA (rrn) operons on the Escherichia coli genome. Inactivation of four rrn operons caused a 2.3-fold increase in th...

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Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Condon, C, French, S, Squires, C, Squires, C L
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC413727/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8223440/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1993.tb06115.x
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