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The IGF-derived tripeptide Gly-Pro-Glu is a weak NMDA receptor agonist

Glutamate acts as the universal agonist at ionotropic glutamate receptors in part because of its high degree of conformational flexibility. Other amino acids and small peptides, however, can activate N-methyl-d-aspartate (NMDA) receptors, albeit usually with lower affinity and efficacy. Here, we exa...

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Bibliografiske detaljer
Main Authors: Vaaga, Christopher E., Tovar, Kenneth R., Westbrook, Gary L.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137256/
https://ncbi.nlm.nih.gov/pubmed/24944213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00290.2014
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