Aldosterone sensitizes connecting tubule glomerular feedback via the aldosterone receptor GPR30

Increasing Na delivery to epithelial Na channels (ENaC) in the connecting tubule (CNT) dilates the afferent arteriole (Af-Art), a process we call connecting tubule glomerular feedback (CTGF). We hypothesize that aldosterone sensitizes CTGF via a nongenomic mechanism that stimulates CNT ENaC via the...

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Bibliografiske detaljer
Main Authors: Ren, YiLin, D'Ambrosio, Martin A., Garvin, Jeffrey L., Leung, Pablo, Kutskill, Kristopher, Wang, Hong, Peterson, Edward L., Carretero, Oscar A.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2014
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137129/
https://ncbi.nlm.nih.gov/pubmed/24966088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00072.2014
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