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A phenome-guided drug repositioning through a latent variable model

BACKGROUND: The phenome represents a distinct set of information in the human population. It has been explored particularly in its relationship with the genome to identify correlations for diseases. The phenome has been also explored for drug repositioning with efforts focusing on the search space f...

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Autori principali: Bisgin, Halil, Liu, Zhichao, Fang, Hong, Kelly, Reagan, Xu, Xiaowei, Tong, Weida
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137076/
https://ncbi.nlm.nih.gov/pubmed/25103881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-15-267
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