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Chk1 Inhibition as a novel therapeutic strategy for treating triple-negative breast and ovarian cancers
BACKGROUND: Chk1 inhibitors are currently in clinical trials as putative potentiators of cytotoxic chemotherapy drugs. Chk1 inhibitors may exhibit single agent anti-tumor activity in cancers with underlying DNA repair, DNA damage response or DNA replication defects. METHODS: Here we describe the cel...
Gorde:
| Egile Nagusiak: | , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
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BioMed Central
2014
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4137066/ https://ncbi.nlm.nih.gov/pubmed/25104095 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-570 |
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