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Survivin transcript variant 2 drives angiogenesis and malignant progression in proneural gliomas

BACKGROUND: The influence of survivin isoforms on outcome in glioblastoma is poorly understood. We analyzed the dominant anti-apoptotic transcript variants of survivin using expression data and modeled them in vivo to determine their impact on glioma formation and progression. METHODS: Using data fr...

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Autori principali: Doucette, Tiffany, Latha, Khatri, Yang, Yuhui, Fuller, Gregory N., Rao, Arvind, Rao, Ganesh
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136894/
https://ncbi.nlm.nih.gov/pubmed/24676140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou034
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