Transferred BCR/ABL DNA from K562 Extracellular Vesicles Causes Chronic Myeloid Leukemia in Immunodeficient Mice

Our previous study showed that besides mRNAs and microRNAs, there are DNA fragments within extracellular vesicles (EVs). The BCR/ABL hybrid gene, involved in the pathogenesis of chronic myeloid leukemia (CML), could be transferred from K562 EVs to neutrophils and decrease their phagocytic activity i...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Cai, Jin, Wu, Gengze, Tan, Xiaorong, Han, Yu, Chen, Caiyu, Li, Chuanwei, Wang, Na, Zou, Xue, Chen, Xinjian, Zhou, Faying, He, Duofen, Zhou, Lin, Jose, Pedro A., Zeng, Chunyu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136837/
https://ncbi.nlm.nih.gov/pubmed/25133686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105200
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados