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Adaptive Evolution and Divergence of SERPINB3: A Young Duplicate in Great Apes

A series of duplication events led to an expansion of clade B Serine Protease Inhibitors (SERPIN), currently displaying a large repertoire of functions in vertebrates. Accordingly, the recent duplicates SERPINB3 and B4 located in human 18q21.3 SERPIN cluster control the activity of different cystein...

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Autores principales: Gomes, Sílvia, Marques, Patrícia I., Matthiesen, Rune, Seixas, Susana
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136820/
https://ncbi.nlm.nih.gov/pubmed/25133778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104935
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