pH regulation is a major determinant in expression of a fungal penicillin biosynthetic gene.

Transcription of the ipnA gene encoding isopenicillin N synthetase, an enzyme of secondary metabolism, is under the control of the pH regulatory system in the fungus Aspergillus nidulans. External alkaline pH or mutations in pacC, the wide domain regulatory gene which mediates pH regulation, overrid...

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Hlavní autoři: Espeso, E A, Tilburn, J, Arst, H N, Peñalva, M A
Médium: Artigo
Jazyk:Inglês
Vydáno: 1993
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC413677/
https://ncbi.nlm.nih.gov/pubmed/8404862
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