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Modular Isotopomer Synthesis of γ-Hydroxybutyric Acid for a Quantitative Analysis of Metabolic Fates

[Image: see text] Herein we report a study combining metabolomics and mass isotopomer analysis used for investigation of the biochemical fate of γ-hydroxybutyric acid (GHB). Using various (13)C incorporation labeling patterns into GHB, we have discovered that GHB is catabolized by previously unknown...

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Autores principales: Sadhukhan, Sushabhan, Zhang, Guo-Fang, Tochtrop, Gregory P.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Chemical Society 2014
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136706/
https://ncbi.nlm.nih.gov/pubmed/24933109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb500380b
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