Synthesis and in Vitro Evaluation of BBB Permeability, Tumor Cell Uptake, and Cytotoxicity of a Series of Carboranylporphyrin Conjugates

[Image: see text] A series of tri[(p-carboranylmethylthio)tetrafluorophenyl]porphyrin conjugates of linear and branched polyamines, glucose, arginine, tri(ethylene glycol), and Tyr-d-Arg-Phe-β-Ala (YRFA) peptide were synthesized. These conjugates were investigated for their BBB permeability in human...

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Hlavní autoři: Bhupathiraju, N. V. S. Dinesh K., Hu, Xiaoke, Zhou, Zehua, Fronczek, Frank R., Couraud, Pierre-Olivier, Romero, Ignacio A., Weksler, Babette, Vicente, M. Graça H.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2014
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136688/
https://ncbi.nlm.nih.gov/pubmed/25029034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm500786c
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