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Quality control of assembly-defective U1 snRNAs by decapping and 5′-to-3′ exonucleolytic digestion
The accurate biogenesis of RNA–protein complexes is a key aspect of eukaryotic cells. Defects in Sm protein complex binding to snRNAs are known to reduce levels of snRNAs, suggesting an unknown quality control system for small nuclear ribonucleoprotein (snRNP) assembly. snRNA quality control may als...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4136611/ https://ncbi.nlm.nih.gov/pubmed/25071210 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1412614111 |
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